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Lack of Motivation Can Impact Brain Function According to New Imaging Study

brain function, lack of motivation

Neuroscientists recently performed a brain imaging study at the Oxford University, England, and the study results showed that a lack of motivation can impact brain function. The team of scientific researchers determined that the brain function in individuals who had a lack of motivation was significantly different from the brain function of individuals who were motivated. Neurology and cognitive neuroscience professor Dr. Masud Husain explained that “We know that in some cases people can become pathologically apathetic, for example after a stroke or with Alzheimer’s disease. Many such patients can be physically capable. Yet they can become so demotivated they won’t be bothered to care for themselves, even though they’re not depressed. By studying healthy people, we wanted to find out whether any differences in their brains might shed light on apathy.”

The imaging study on brain function and lack of motivation involved 40 volunteers, all who were healthy. The volunteers were given a questionnaire on motivation and then played a game that involved reward and effort while their brain function was scanned. Those with a lack of motivation were less likely to choose small rewards that required big effort, and more likely to choose large rewards that required little effort on their part. The imaging showed that the premotor cortex in people with a lack of motivation was more active, and this surprised the researchers. Dr. Husain said “We expected to see less activity because they were less likely to accept effortful choices but we found the opposite. We thought that this might be because their brain structure is less efficient, so it’s more of an effort for apathetic people to turn decisions into actions. Using our brain scanning techniques, we found that connections in the front part of the brains of apathetic people are less effective. The brain uses around a fifth of the energy you’re burning each day. If it takes more energy to plan an action, it becomes more costly for apathetic people to make actions. Their brains have to make more effort.”

How Does Schizophrenia Affect Brain Function?

schizophrenia, brain function

Schizophrenia, a serious and sometimes extremely devastating mental disorder, is a condition that has no cure right now. Thanks to advances in modern medicine and imaging technology scientists today know that people who suffer from schizophrenia tend to have brain function that is abnormal in certain respects. Imaging scans of those with the mental disorder and with control scans from patents who have no mental illness show that different areas of the brain are active in those who have schizophrenia. People who have this condition may suffer from chemical imbalances with neurotransmitters, complex chemicals that allow communication between brain cells and chemical systems in the brain and body. Some scientists believe that the neurotransmitters glutamate and dopamine may be involved in schizophrenia but this is still being tested and is not proven yet.

In addition to differences in brain function many people with schizophrenia also have abnormalities in the structure of the brain. When images of normal and schizophrenic brains are compared there are small but very discernible differences in the structure of the brain. It is important to note that some with schizophrenia may not have these physical abnormalities in the brain structure, and some without this condition may also have the same structural abnormalities though. This means that simply looking at brain scans can not predict who will develop the condition. Some neurobiologists theorize that schizophrenia may result from inappropriate connections which are formed by neurons in the fetal brain, and these are activated during puberty when the drastic brain changes that occur during this growth phase affect the faulty connections.